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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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FAQs

Can I take Cialis with alcohol?

It is not recommended to take Cialis with alcohol while using Cialis, as both the medication and alcohol can interact. While this may be preferable for sensitive individuals, it should not be taken for longer than 6 hours.oway.able/atar/ flashed/fotoose_odcast/stocks_photos_odcast

Is Cialis with nitrates or nitroglycerin more effective?

While Cialis can be used as a short-term treatment, it is generally not recommended for use with nitrates or nitroglycerin. A higher dose of tadalafil can be used in those with high blood pressure or an underlying health condition that increases the risk of complications like erectile dysfunction.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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Be sure to take this medication at least 2 hours before or 6 hours after taking any other medications. This may keep some herbs from interacting with Cialis, so be sure to inform your doctor about any other medications you are taking.

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Cialis medicine is available in 5mg.

The Pakistan Authority of Medical Sciences and Dental Sciences (PAAS) has approved the purchase of Cialis Pills to the extent that it is required by the Ministry of Health (MOH).

The approval is based on the analysis of data from the national population-based survey of the PAAS’s population.

“The approval of Cialis Pills is the result of the PAAS’s assessment of the PAAS’s population and its population size,” the Authority said.

“As per the analysis, the PAAS is required by the Ministry of Health (MOH) to take into account the following factors: population size, population density, population impact, population trends and population size.”

“The PAAS has informed PAAS that, the approval of Cialis Pills to the extent that it is required by the Ministry of Health (MOH) to take into account the following factors: population size, population density, population impact, population trends and population size.”

The PAAS also said that Cialis Pills would be available to customers in the market in the following regions:

North:

South:

Mumbai:

Peshawar:

A close monitoring and analysis of the PAAS’s population data in Pakistan was conducted to address the aforementioned factors. The PAAS’s decision to approves Cialis Pills in the region was taken as the result of its assessment of population size, population density, population impact, population trends and population size.

Cialis Pills, the active pharmaceutical ingredient of Cialis, is indicated for the treatment of erectile dysfunction (ED) in men and impotence in women. It is also indicated for the treatment of benign prostatic hyperplasia (BPH) in men and the treatment of prostate cancer in women. The treatment is also indicated in men and women who are at an increased risk of urinary tract infections. Cialis has been approved for use in Pakistan in the past.

Cialis Pills is used primarily in the treatment of ED, a condition where an erection lasts for multiple hours, and the symptoms include frequent urination and frequent sexual intercourse. The treatment of ED can be administered by a doctor, and the dosage can be adjusted based on the patient’s age, sex life, overall health, and response to treatment.

The PAAS has approved Cialis for sale in the following regions:

A close monitoring and analysis of the PAAS’s population-based survey in Pakistan was conducted to address the aforementioned factors.

The PAAS has advised that Cialis Pills to be sold in the following regions:

Cialis is available for sale in the following regions:

Cialis is a phosphodiesterase type 5 inhibitor (PDE5i) used primarily for the treatment of erectile dysfunction (ED) in men and impotence in women.